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The Saccharomyces cerevisiae nuclear gene A R G 8 encodes an enzyme that catalyzes a key step in biosynthesis of the amino acid arginine. This protein is normally synthesized on cytoplasmic ribosomes, but then is transported into mitochondria, where the enzyme conducts its functions. In 1996, T. D. Fox and his colleagues constructed a strain of yeast in which a gene encoding the Arg8 protein was itself moved into mitochondria, where functional protein could be synthesized on mitochondrial riboso
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