STEMart announces the expansion of its genetic toxicology capabilities with the In Vivo Rat Micronucleus Test services.
The cytokinesis-block micronucleus test (MNT), as a marker of chromosomal mutagen sensitivity, was applied in a number of studies enrolling breast cancer (BC) patients and subjects with known or ...
Radiation Research, Vol. 180, No. 3 (September 2013), pp. 284-291 (8 pages) The frequency of binucleated cells containing one or more micronuclei (MNBN cells) in cytokinesis-blocked peripheral blood ...
The induction of micronuclei is a key characteristic of genotoxic compounds; for example, clastrogens produce DNA strand breakage while aneugens interfere with chromosome segregation. As a result, ...
Asbestos and other mineral fibers have long been known to induce lung cancer and mesothelioma. However, the primary mechanisms of fiber-induced carcinogenesis still remain unclear. We investigated the ...
Within the hallowed walls of the cell, conflict simmers; a tenuous peace, and perhaps its very survival, rest on the slimmest of margins. Housed within the cell’s inner sanctum – the nucleus – is its ...