Scientists from Children’s Medical Research Institute (CMRI) have successfully tested adeno-associated viral vector-based (AAV) gene therapies in whole human livers in the lab. The study, which is ...

Dr. Vadim Jucaud's lab at the Terasaki Institute has developed a vascularized liver tissueoid-on-a-chip (LToC) platform that ...

Scientists have identified a hidden barrier that prevents immunotherapy from working against a rare liver cancer. Immunotherapy, which activates the body’s own immune system to kill cancer cells, has ...

Creating a drug that might help treat or cure a health condition in humans is a long, complex process. After developing a ...

A new study from Karolinska Institutet in Sweden reveals that immune cells in the liver react to high cholesterol levels and eat up excess cholesterol that can otherwise cause damage to arteries. The ...

For nearly 40 years, organ transplants in the United States have been directed by a single nonprofit called the United Network for Organ Sharing — UNOS. Critics say UNOS has come to be plagued by ...

More than 100 million people in the United States suffer from metabolic dysfunction-associated steatotic liver disease (MASLD), characterized by a buildup of fat in the liver. This condition can lead ...

The connection between the human liver and the intestine is unique, and the “gut-liver axis” plays a vital role in regulating liver disease pathology. When homeostasis is disturbed, changes in dietary ...

WASHINGTON — The U.S. is developing new safeguards for the organ transplant system after a government investigation found a Kentucky group continued preparations for organ donation by some patients ...

Inequities in access to transplant are in part due to the nature and organization of the selection process. The limited organ supply and rising incidence of end-stage organ disease have resulted in a ...