Creative depiction of the epigenetic editing toolkit: each building represents the epigenetic state of a single gene (dark windows are silenced genes, lit up windows are active genes). The crane ...

In a study published in Nature Biotechnology, researchers have enhanced the genome editing capabilities of Obligate Mobile Element Guided Activity (OMEGA)-IscB, an endonuclease protein, through ...

Epigenetics refer to DNA modifications that may affect phenotype but don’t alter the nucleotide sequence itself. Epigenetic changes can often be passed down generations, hence the Greek prefix “epi”, ...

Epigenome editing has undergone something of a renaissance in recent years, but scientists have been using basic gene-modulation tools for much longer. Two of the earliest were transcriptional ...

CRISPR-based therapy is a transformative approach to medicine that allows for targeted changes to the genome by directly addressing the source of disease, or to the epigenome through silencing of ...

As the climate crisis intensifies, traditional genetic breeding alone may not keep pace with the rapid shifts in environmental stressors. While the ...