Why do some people with amyloid plaques decline, while others do not? In the May 29 Nature Medicine, researchers led by Tharick Pascoal at the University of Pittsburgh laid some of the blame on ...

Habenular astrocyte acidification in the anxiogenic environment. (A) The fluorescence sensor protein E2GFP is sensitive to changes in intracellular pH. The green emission in response to purple light ...

Some brain disorders are straightforward, such as the direct frontal lobe assault of a concussion or traumatic brain injury. Others, like Alexander disease, are akin to guerrilla warfare. Patients ...

MADISON, Wis. -- A pioneer in the study of neural cells revealed today (Oct. 23, 2018) how a single mutation affecting the most common protein in a supporting brain cell produces devastating, fibrous ...

When epileptic patients suffer seizures, their brain is undergoing repetitive and excessive neuronal firing. But what triggers this has stumped scientists for years. Now, researchers have used ...

In a recent study published in Nature, researchers investigated whether glutamatergic gliotransmission was mediated by specialized astrocytes in the central nervous system. Study: Specialized ...

The potential effects of astrocyte dysfunction in neurodegenerative diseases are summarized in Figure 2. AD is characterized clinically by cognitive loss in two or more domains, including memory, ...

Researchers have shown that astrocytes in the mouse brain exhibit an acid response with intensified epileptic seizures. The astrocytes' acid response could lead to the amplification of excitatory ...

Move over, amyloid, reactive astrocytes and activated microglia may be the main drivers of the Alzheimer’s disease pathological cascade. In the November 6 Nature Neuroscience, scientists led by Pedro ...

Some brain disorders are straightforward, such as the direct frontal lobe assault of a concussion or traumatic brain injury. Others, like Alexander disease, are akin to guerilla warfare. Patients ...